Hundreds of millions of women live longer than men yet spend more years in poor health. The biology driving this disparity is rooted in ovarian aging and the menopausal transition, and it remains one of the most underfunded areas in medicine. We are raising $250,000 by September 1, 2026, to fund the science that closes that gap — for mothers, daughters, and women everywhere.
Women live longer than men on average, but spend more years in poor health. A single biological transition sits at the center of that disparity: menopause. The ovaries are among the fastest-aging organs in the body, and the hormonal cascade that follows their decline reverberates across every major system. The risks below are not incidental: they are downstream consequences of a process medicine has been chronically underprepared to address.
The pervasive funding gap is a systemic symptom: for most of modern medical history, the female body was not the default. Women were excluded from research, undertested in clinical trials, and underrepresented in the data that shapes how disease is diagnosed and treated. The consequences of that exclusion are still being paid today.
Prior to the NIH Revitalization Act, women were routinely excluded from research, leaving decades of drug dosages, diagnostic criteria, and treatment protocols calibrated entirely to male physiology.
Disease presentation, progression, and response to treatment often differ significantly between sexes. When research is built on male data, those differences go undetected, and women receive care designed for someone else's biology.
For most of pharmaceutical history, drugs were approved without distinguishing how they perform across sexes. Women metabolize many drugs differently, yet dosing guidelines were written without them.
Fund the science to slow ovarian aging, delay menopause, and close the health gap it creates in women's lives.
Fund This WorkProgress cannot rely on funding isolated therapies alone. We fund three coordinated pillars simultaneously — measurement, biological understanding, and early-stage intervention — targeting the full arc of women's reproductive aging. Our scientific leadership and advisory structure is led by women working at the frontier of this field.
"The science to close this gap exists. What's needed now is the commitment to fund it."
Dr. Corlianò is a distinguished biologist with over eight years of preclinical and clinical research experience across leading institutions in Europe and Asia. A SINGA PhD scholar at the National University of Singapore and founder of OSbiome, she leads LSF's scientific evaluation, identifying high-impact projects in aging research and ensuring every funded initiative meets rigorous standards of scientific merit and translational potential.
Through our scientific review process, we have identified a portfolio of high-impact projects across all three pillars, ready for immediate funding. Click any pillar to explore the work.
Menopause is still diagnosed largely from symptoms and menstrual history — educated guesswork, not precision medicine. This work develops a "menopause clock" alongside non-invasive molecular sensors for real-time, cycle-by-cycle tracking of reproductive biomarkers. The goal: detect when a woman's biology begins to shift, early enough to act.
These projects map the biological mechanisms connecting reproductive aging to broader systemic decline — in cognition, metabolism, and whole-body aging. This is the science of understanding the "why" before the "how to fix it."
Rather than waiting for decline and treating downstream consequences, these projects target the biological source directly — representing a new frontier in treating reproductive aging as a modifiable condition, not a fixed fate.
Every donor deserves to know exactly where their money goes and what it achieves. We commit to keeping you informed at every stage: from funds raised to research milestones.
Every donor receives a monthly update on total funds raised and campaign progress — written in plain language, not jargon. You will always know where the campaign stands.
As funded projects hit key milestones — from study launch to interim findings to publication — we share those moments directly with the community that made them possible.
Every dollar donated goes directly to research. Our operating costs are funded separately — your gift is never diluted by overhead. This is a standing, unconditional commitment.
Your gift funds science across all three pillars simultaneously — at the early stage where targeted capital unlocks disproportionate progress.
Fund This ResearchWomen's health research has been underfunded for too long, and closing that gap requires more than institutional dollars. Whether you're in our network or finding us for the first time, there is a meaningful role for you in this campaign.
Donate at whatever level resonates. 100% of every dollar goes directly to research — no overhead, no dilution.
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Share why women's health research matters to you. Personal stories move people in ways data alone cannot. Post, write, speak, and tag us.
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If you are a communicator, connector, or advocate who wants to play a more active role in this campaign, we want to hear from you.
Ready to give one of these? We'd love to connect.
info@longevity.foundationEvery dollar you give goes directly to the research portfolio — no overhead, no dilution.
We are raising $250,000 by September 1, 2026. When the campaign goal is reached, our partners at LongeVC will contribute an additional $25,000 — unlocked by the collective effort of everyone who gives.
Questions? info@longevity.foundation
We partner with donors at every level, from first-time contributors to transformational funders who want to shape the future of longevity science. Each tier carries meaningful recognition and engagement.
View Donor TiersTransformational Gifts · $500K+
"Your legacy isn't just what you leave behind. It's what you set in motion."
— Joshua C. Herring, President & CEO, Longevity Science Foundation
The LSF Founders Fund offers named grant calls, first investment rights into research spinouts, co-investment alongside LongeVC, and a permanent place in the history of longevity science.
Speak With Our TeamThe science exists. The projects are ready. What's needed now is the capital to put it in motion and the community of people who believe this work is long overdue.